Screening of Maternal Serum for Fetal Down's Syndrome in the First Trimester

1998236 citationsJournal Articlebronze Open Access

Authors

James E. Haddow · Foundation for Blood Research

Glenn E. Palomaki

Abstract

Screening for Down's syndrome in the first trimester is feasible, with use of measurements of pregnancy-associated protein A and either hCG or its free beta subunit in maternal serum.

Topics & Keywords

Prenatal Screening and Diagnostics Parvovirus B19 Infection Studies

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 338, Issue 14, pp. 955-962

DOI: 10.1056/nejm199804023381404

Field-Weighted Citation Impact: 37.12