Epstein–Barr virus microRNAs and lung cancer

201126 citationsJournal Articlehybrid Open Access

Authors

Jill Koshiol · National Cancer Institute

Margaret L. Gulley · University of North Carolina at Chapel Hill

Yingdong Zhao · National Institutes of Health

Maurizia Rubagotti · University of Milan

Francesco M. Marincola · National Institutes of Health

Melissa Rotunno · National Cancer Institute

Weihua Tang

Abstract

In a comprehensive evaluation of EBV miRNA, DNA, RNA, and protein in lung cancer, we found little evidence of EBV in lung tumour tissue. Discrepancies between microarray- and qPCR-based strategies highlight the difficulty of validating molecular markers of disease. Our results do not support a role of EBV in lung cancer.

Topics & Keywords

Viral-associated cancers and disorders Polyomavirus and related diseases Cancer-related molecular mechanisms research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: British Journal of Cancer

Volume 105, Issue 2, pp. 320-326

DOI: 10.1038/bjc.2011.221

Field-Weighted Citation Impact: 0.56