Treating Childhood Acute Lymphoblastic Leukemia without Cranial Irradiation

20091,212 citationsJournal Articlebronze Open Access

Authors

Ching-Hon Pui · St. Jude Children's Research Hospital

Dario Campana · University of Tennessee Health Science Center

Deqing Pei · St. Jude Children's Research Hospital

W. Paul Bowman · Cook Children's Medical Center

John T. Sandlund · University of Tennessee Health Science Center

Sue C. Kaste · University of Tennessee Health Science Center

Raul C. Ribeiro

Abstract

With effective risk-adjusted chemotherapy, prophylactic cranial irradiation can be safely omitted from the treatment of childhood ALL. (ClinicalTrials.gov number, NCT00137111.)

Topics & Keywords

Acute Lymphoblastic Leukemia research Childhood Cancer Survivors' Quality of Life Neuroblastoma Research and Treatments

UN Sustainable Development Goals

No poverty

Publication Details

Published in: New England Journal of Medicine

Volume 360, Issue 26, pp. 2730-2741

DOI: 10.1056/nejmoa0900386

Field-Weighted Citation Impact: 87.34