Baicalein Reduces Inflammatory Process in a Rodent Model of Diabetic Retinopathy

2009157 citationsJournal Article

Authors

Li-ping Yang · Peking University

Hui-li Sun · Guangzhou University

Le-meng Wu · Peking University Third Hospital

Xiu‐juan Guo · Peking University

Hongliang Dou · Peking University Third Hospital

Mark O.M. Tso · Johns Hopkins Medicine

Lin Zhao ·

Abstract

Inflammatory process, characterized by microglial activation and Müller cells dysfunction, was implicated in STZ-induced diabetic retinopathy. Baicalein treatment ameliorated inflammatory process, and therefore inhibited vascular abnormality and neuron loss in diabetic retinas.

Topics & Keywords

Flavonoids in Medical Research Retinal Diseases and Treatments Glaucoma and retinal disorders

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Investigative Ophthalmology & Visual Science

Volume 50, Issue 5, pp. 2319-2319

DOI: 10.1167/iovs.08-2642

Field-Weighted Citation Impact: 8.85