Randomized, blinded trial of weekend vs daily prednisone in Duchenne muscular dystrophy

2011161 citationsJournal Articlebronze Open Access

Authors

Diana M. Escolar

Lauren P. Hache

Paula R. Clemens

Avital Cnaan

Craig M. McDonald

Viswanathan Venkataraman

Andrew J. Kornberg

T. E. Bertoríni

Yoram Nevo

Timothy Lotze · Baylor College of Medicine

Alan Pestronk

Monique M. Ryan

Abstract

This study provides Class I evidence that weekend prednisone dosing is as safe and effective as daily prednisone in preserving muscle strength and preventing body mass index increases in boys with DMD over a 12-month period.

Topics & Keywords

Muscle Physiology and Disorders Eating Disorders and Behaviors Exercise and Physiological Responses

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Neurology

Volume 77, Issue 5, pp. 444-452

DOI: 10.1212/wnl.0b013e318227b164

Field-Weighted Citation Impact: 5.05