Statins and the Risk of Colorectal Cancer

2005823 citationsJournal Article

Authors

Jenny N. Poynter · University of Michigan–Ann Arbor

Stephen B. Gruber · University of Michigan–Ann Arbor

Peter Higgins · University of Michigan–Ann Arbor

Ronit Almog · Carmel Medical Center

Joseph D. Bonner · University of Michigan–Ann Arbor

Hedy S. Rennert · Technion – Israel Institute of Technology

Marcelo Low

Abstract

The use of statins was associated with a 47 percent relative reduction in the risk of colorectal cancer after adjustment for other known risk factors. Because the absolute risk reduction is likely low, further investigation of the overall benefits of statins in preventing colorectal cancer is warranted.

Topics & Keywords

Cancer, Lipids, and Metabolism Lipoproteins and Cardiovascular Health Inflammatory mediators and NSAID effects

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 352, Issue 21, pp. 2184-2192

DOI: 10.1056/nejmoa043792

Field-Weighted Citation Impact: 27.13