Efficient Synthesis of Fluoren-9-ones by the Palladium-Catalyzed Annulation of Arynes by 2-Haloarenecarboxaldehydes

200863 citationsJournal Article

Authors

Richard C. Larock · Iowa State University

Abstract

Fluoren-9-ones and derivatives are readily prepared in good yields by the annulation of in situ generated arynes by 2-haloarenecarboxaldehydes in the presence of a palladium catalyst.

Topics & Keywords

Cyclization and Aryne Chemistry Synthesis and Biological Activity Chemical synthesis and alkaloids

Publication Details

Published in: The Journal of Organic Chemistry

Volume 73, Issue 17, pp. 6679-6685

DOI: 10.1021/jo8009215

Field-Weighted Citation Impact: 2.72

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Efficient Synthesis of Fluoren-9-ones by the Palladium-Catalyzed Annulation of Arynes by 2-Haloarenecarboxaldehydes

Authors

Abstract

Topics & Keywords

Publication Details