Validation of VKORC1 and CYP2C9 genotypes on interindividual warfarin maintenance dose: a prospective study in Chinese patients

2009152 citationsJournal Article

Authors

Sheng‐Wen Huang · Southern Medical University

Haisheng Chen · Gaozhou People's Hospital

Xian-Qun Wang

Ling Huang · Laboratoire de Chimie

Dingli Xu · Institute of Cardiology

Xiaojia Hu · Laboratoire de Chimie

Zhihui Huang · Gaozhou People's Hospital

Abstract

A pharmacogenetics-based dosing algorithm has been developed for improvement in the time to reach the stable dosing of warfarin. This model may be useful in helping the clinicians to prescribe warfarin with greater safety and efficiency.

Topics & Keywords

Pharmacogenetics and Drug Metabolism Hormonal Regulation and Hypertension Eicosanoids and Hypertension Pharmacology

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Pharmacogenetics and Genomics

Volume 19, Issue 3, pp. 226-234

DOI: 10.1097/fpc.0b013e328326e0c7

Field-Weighted Citation Impact: 16.00