Targeting Rat Brainstem Glioma Using Human Neural Stem Cells and Human Mesenchymal Stem Cells

2009113 citationsJournal Articlebronze Open Access

Authors

Do‐Hun Lee · University of British Columbia Hospital

Yong‐Oon Ahn · University of British Columbia Hospital

Seung Up Kim · University of British Columbia Hospital

Kyu‐Chang Wang · University of British Columbia Hospital

Byung-Kyu Cho · University of British Columbia Hospital

Ji Hoon Phi · University of British Columbia Hospital

In Ho Park

Abstract

The brainstem glioma-tropic migratory capacities of MSCs from various sources were similar to those of NSCs. Genetically engineered NSCs show therapeutic efficacy against brainstem gliomas.

Topics & Keywords

Mesenchymal stem cell research Neurogenesis and neuroplasticity mechanisms MicroRNA in disease regulation

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Clinical Cancer Research

Volume 15, Issue 15, pp. 4925-4934

DOI: 10.1158/1078-0432.ccr-08-3076

Field-Weighted Citation Impact: 5.20