Small study effects in meta-analyses of osteoarthritis trials: meta-epidemiological study

2010557 citationsReviewhybrid Open Access

Authors

Eveline Nüesch · University Hospital of Bern

Sven Trelle · University of Bern

Stephan Reichenbach · University of Bern

Anne WS Rutjes · Mario Negri Sud Foundation

B. Tschannen · University of Bern

Doug Altman · University of Oxford

Matthias Egger ·

Abstract

Small study effects can often distort results of meta-analyses. The influence of small trials on estimated treatment effects should be routinely assessed.

Topics & Keywords

Meta-analysis and systematic reviews Musculoskeletal pain and rehabilitation Clinical practice guidelines implementation

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: BMJ

Volume 341, Issue jul16 1, pp. c3515-c3515

DOI: 10.1136/bmj.c3515

Field-Weighted Citation Impact: 30.96