Controlled PEGylation of Monodisperse Fe₃O₄ Nanoparticles for Reduced Non‐Specific Uptake by Macrophage Cells

A dopamine-PEG based ligand is synthesized and used to stabilize monodisperse 9 nm Fe3O4 nanoparticles in physiological conditions and against non-specific uptake by macrophage cells. Such stable nanoparticles can be used to enhance the efficiency in target-specific drug delivery and to increase the signal-to-noise ratio in magnetic resonance imaging (MRI). Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2089/2007/c1975_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.