Reversal of transtentorial herniation with hypertonic saline

2008292 citationsJournal Article

Authors

Matthew A. Koenig · Johns Hopkins University

Mersine A. Bryan · Johns Hopkins University

Jerzy Lewin · Johns Hopkins University

Marek A. Mirski · Johns Hopkins University

Romer Geocadin · Johns Hopkins University

Robert D. Stevens · Johns Hopkins University

Abstract

Treatment with 23.4% saline was associated with rapid reversal of transtentorial herniation (TTH) and reduced intracranial pressure, and had few adverse effects. Outcomes of TTH were poor, but medical reversal may extend the window for adjunctive treatments.

Topics & Keywords

Neurosurgical Procedures and Complications Traumatic Brain Injury and Neurovascular Disturbances Cerebrospinal fluid and hydrocephalus

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Neurology

Volume 70, Issue 13, pp. 1023-1029

DOI: 10.1212/01.wnl.0000304042.05557.60

Field-Weighted Citation Impact: 11.27