Plasma Aβ40 and Aβ42 and Alzheimer’s disease

2003432 citationsJournal Article

Authors

R. Mayeux · Mayville State University

Lawrence S. Honig · Mayville State University

Ming-X Tang · Mayville State University

Jennifer J. Manly · Mayville State University

Yaakov Stern · Mayville State University

Nicole Schupf · Mayville State University

Pankaj Mehta ·

Abstract

Plasma A[beta]40 and A[beta]42 increase with age and are strongly correlated with each other. Plasma A[beta]40 and A[beta]42 levels are elevated in some patients before and during the early stages of AD but decline thereafter. High plasma A[beta]42 levels may also be associated with mortality in patients with AD.

Topics & Keywords

Alzheimer's disease research and treatments Dementia and Cognitive Impairment Research GDF15 and Related Biomarkers

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Neurology

Volume 61, Issue 9, pp. 1185-1190

DOI: 10.1212/01.wnl.0000091890.32140.8f

Field-Weighted Citation Impact: 9.21