Dopamine Neuron Stimulating Actions of a GDNF Propeptide

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Authors

Luke H. Bradley · University of Kentucky

Josh Fuqua · University of Kentucky

April Richardson · University of Kentucky

Jadwiga Turchan‐Cholewo · University of Kentucky

Yi Ai · University of Kentucky

Kristen A. Kelps · University of Kentucky

John D. Glass ·

Abstract

Collectively, these data support that DNSP-11 exhibits potent neurotrophic actions analogous to GDNF, making it a viable candidate for a PD therapeutic. However, it likely signals through pathways that do not directly involve the GFRalpha1 receptor.

Topics & Keywords

Nerve injury and regeneration Autism Spectrum Disorder Research Genetics and Neurodevelopmental Disorders

Publication Details

Published in: PLoS ONE

Volume 5, Issue 3, pp. e9752-e9752

DOI: 10.1371/journal.pone.0009752

Field-Weighted Citation Impact: 1.29

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Dopamine Neuron Stimulating Actions of a GDNF Propeptide

Authors

Abstract

Topics & Keywords

Publication Details