MicroRNA Expression, Survival, and Response to Interferon in Liver Cancer

2009806 citationsJournal Articlebronze Open Access

Authors

Junfang Ji · National Institutes of Health

Jiong Shi · National Cancer Institute

Anuradha Budhu · Center for Cancer Research

Zhipeng Yu · Center for Cancer Research

Marshonna Forgues · National Cancer Institute

Stéphanie Roessler · National Cancer Institute

Stefan Ambs ·

Abstract

The expression patterns of microRNAs in liver tissue differ between men and women with hepatocellular carcinoma. The miR-26 expression status of such patients is associated with survival and response to adjuvant therapy with interferon alfa.

Topics & Keywords

MicroRNA in disease regulation Cancer-related molecular mechanisms research Circular RNAs in diseases

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 361, Issue 15, pp. 1437-1447

DOI: 10.1056/nejmoa0901282

Field-Weighted Citation Impact: 28.26