Prevention of Recurrent Preterm Delivery by 17 Alpha-Hydroxyprogesterone Caproate

20031,558 citationsJournal Articlebronze Open Access

Authors

Paul J. Meis · Wake Forest University

Mark A. Klebanoff · Health and Human Development (2HD) Research Network

Elizabeth Thom

Mitchell P. Dombrowski · Wayne State University

Baha M. Sibai · University of Tennessee at Knoxville

Atef H. Moawad · University of Chicago

Catherine Y. Spong · Health and Human Development (2HD) Research Network

Abstract

Weekly injections of 17P resulted in a substantial reduction in the rate of recurrent preterm delivery among women who were at particularly high risk for preterm delivery and reduced the likelihood of several complications in their infants.

Topics & Keywords

Preterm Birth and Chorioamnionitis Pregnancy-related medical research Reproductive Physiology in Livestock

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 348, Issue 24, pp. 2379-2385

DOI: 10.1056/nejmoa035140

Field-Weighted Citation Impact: 35.54