Evaluation of a Direct, Rapid Immunohistochemical Test for Rabies Diagnosis

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Authors

Tiziana Lembo · University of Edinburgh

Michael Niezgoda · Centers for Disease Control and Prevention

Andrés Velasco-Villa · Centers for Disease Control and Prevention

Sarah Cleaveland · University of Edinburgh

Eblate Ernest · Tanzania Wildlife Research Institute

Charles E. Rupprecht · Centers for Disease Control and Prevention

Abstract

A direct rapid immunohistochemical test (dRIT) was evaluated under field and laboratory conditions to detect rabies virus antigen in frozen and glycerol-preserved field brain samples from northwestern Tanzania. Compared to the direct fluorescent antibody test, the traditional standard in rabies diagnosis, the dRIT was 100% sensitive and specific.

Topics & Keywords

Rabies epidemiology and control Streptococcal Infections and Treatments Microbial infections and disease research

Publication Details

Published in: Emerging infectious diseases

Volume 12, Issue 2, pp. 310-313

DOI: 10.3201/eid1202.050812

Field-Weighted Citation Impact: 8.01

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Evaluation of a Direct, Rapid Immunohistochemical Test for Rabies Diagnosis

Authors

Abstract

Topics & Keywords

Publication Details