The use of an imaging proportional counter in macromolecular crystallography

A multiwire proportional chamber known as an imaging proportional counter has been used to collect X-ray intensity data for the determination of several structures by molecular replacement or difference Fourier analysis and has provided data for numerous other macromolecular crystallographic projects. Results obtained with an imaging proportional counter mounted on a rotating-anode X-ray generator indicate that the detector produces accurate intensity information and that its reliability is high.