Synthesis of Imidazol-2-ylidenes by Reduction of Imidazole-2(3<i>H</i>)-thiones

1993650 citationsJournal Article

Authors

Norbert Kühn · University of Duisburg-Essen

Thomas Kratz · University of Duisburg-Essen

Abstract

An improved synthesis of the title compounds is reported. Reaction of the N,N-dialkylthioureas 1 with 3-hydroxy-2-butanone gives the imidazole-2(3H)-thiones 2 which on treatment with potassium in boiling tetrahydrofuran give the imidazol-2-ylidenes 3 in excellent yields.

Topics & Keywords

Synthesis of heterocyclic compounds Synthesis and Reactions of Organic Compounds Synthesis and Reactivity of Sulfur-Containing Compounds

UN Sustainable Development Goals

Clean water and sanitation

Publication Details

Published in: Synthesis

Volume 1993, Issue 06, pp. 561-562

DOI: 10.1055/s-1993-25902

Field-Weighted Citation Impact: 8.62