Protection by Trehalose of DNA from Radiation Damage

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Authors

Koichi Yoshinaga · Shizuoka University

Hiroe Yoshioka · Shizuoka University

Hiromu Kurosaki · Shizuoka University

Miyuki Hirasawa · Shizuoka University

Masahiro Uritani · Shizuoka University

K. Hasegawa · Shizuoka University

Abstract

The most serious damage to cells exposed to radiation is attributed mostly to effects on the structure of cellular DNA. We found that trehalose protects DNA from irradiation. In the presence of 10 mM trehalose, DNA can be protected from about 4 times higher doses of beta- and gamma-ray irradiation. The protective effect increases with the amount of the sugar. Other disaccharides, sucrose, and maltose had similar effects.

Topics & Keywords

Plant Genetic and Mutation Studies

Publication Details

Published in: Bioscience Biotechnology and Biochemistry

Volume 61, Issue 1, pp. 160-161

DOI: 10.1271/bbb.61.160

Field-Weighted Citation Impact: 0.52

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Protection by Trehalose of DNA from Radiation Damage

Authors

Abstract

Topics & Keywords

Publication Details