Genomic occupancy of Runx2 with global expression profiling identifies a novel dimension to control of osteoblastogenesis

2014147 citationsJournal Articlegold Open Access

Authors

Hai Wu · University of Vermont

Troy W. Whitfield · University of Massachusetts Chan Medical School

Jonathan A. R. Gordon · University of Vermont

Jason R. Dobson · Brown University

Phillip W.L. Tai · University of Vermont

André J. van Wijnen · Mayo Clinic

Janet L. Stein ·

Abstract

Our data establish that Runx2 interactions with chromatin across the genome reveal novel genes, pathways and transcriptional mechanisms that contribute to the regulation of osteoblastogenesis.

Topics & Keywords

Bone Metabolism and Diseases RNA Research and Splicing Molecular Biology Techniques and Applications

Publication Details

Published in: Genome biology

Volume 15, Issue 3, pp. R52-R52

DOI: 10.1186/gb-2014-15-3-r52

Field-Weighted Citation Impact: 7.27

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Genomic occupancy of Runx2 with global expression profiling identifies a novel dimension to control of osteoblastogenesis

Authors

Abstract

Topics & Keywords

Publication Details