Randomized, double-blind comparison of immediate-release omeprazole oral suspension versus intravenous cimetidine for the prevention of upper gastrointestinal bleeding in critically ill patients

2005160 citationsJournal Article

Authors

Steven A. Conrad · Louisiana State University in Shreveport

Andrea Gabrielli · Jacobson Holman (United States)

Benjamin D. Margolis · Jacobson Holman (United States)

Andrew A. Quartin · Jacobson Holman (United States)

J. Steven Hata · Jacobson Holman (United States)

William O. Frank · Jacobson Holman (United States)

Robert Bagin

Abstract

Immediate-release omeprazole suspension is effective in preventing upper gastrointestinal bleeding and more effective than intravenous cimetidine in maintaining gastric pH of >4 in critically ill patients.

Topics & Keywords

Nosocomial Infections in ICU Antibiotics Pharmacokinetics and Efficacy Pneumonia and Respiratory Infections

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Critical Care Medicine

Volume 33, Issue 4, pp. 760-765

DOI: 10.1097/01.ccm.0000157751.92249.32

Field-Weighted Citation Impact: 10.23