Polysulfides Link H <sub>2</sub> S to Protein Thiol Oxidation

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Authors

Romy Greiner · German Cancer Research Center

Zoltán Pálinkás · National Institute of Oncology

Katrin Bäsell · Universität Greifswald

Dörte Becher · Universität Greifswald

Haike Antelmann · Universität Greifswald

Péter Nagy · National Institute of Oncology

Tobias P. Dick ·

Abstract

This study suggests that the effects that have been attributed to H2S in previous reports may in fact have been mediated by polysulfides. It also supports the notion that sulfane sulfur rather than sulfide is the actual in vivo agent of H2S signaling.

Topics & Keywords

Sulfur Compounds in Biology Industrial Gas Emission Control Air Quality and Health Impacts

UN Sustainable Development Goals

Industry, innovation and infrastructure

Publication Details

Published in: Antioxidants and Redox Signaling

Volume 19, Issue 15, pp. 1749-1765

DOI: 10.1089/ars.2012.5041

Field-Weighted Citation Impact: 25.14