Plasma Concentration of Interleukin-6 and the Risk of Future Myocardial Infarction Among Apparently Healthy Men

20002,414 citationsJournal Articlegreen Open Access

Authors

Paul M. Ridker · Brigham and Women's Hospital

Nader Rifai · Brigham and Women's Hospital

Meir J. Stampfer · Brigham and Women's Hospital

Charles H. Hennekens · Brigham and Women's Hospital

Abstract

In apparently healthy men, elevated levels of IL-6 are associated with increased risk of future MI. These data thus support a role for cytokine-mediated inflammation in the early stages of atherogenesis.

Topics & Keywords

Adipokines, Inflammation, and Metabolic Diseases Atherosclerosis and Cardiovascular Diseases Cardiovascular Disease and Adiposity

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Circulation

Volume 101, Issue 15, pp. 1767-1772

DOI: 10.1161/01.cir.101.15.1767

Field-Weighted Citation Impact: 71.54