C-Reactive Protein, Interleukin-6, and Soluble Adhesion Molecules as Predictors of Progressive Peripheral Atherosclerosis in the General Population

2005427 citationsJournal Article

Authors

Ioanna Tzoulaki · University of Aberdeen

Gordon Murray · University of Aberdeen

Amanda Lee · University of Aberdeen

Ann Rumley · University of Aberdeen

Gordon Lowe · University of Aberdeen

F. Gerald R. Fowkes · University of Aberdeen

Abstract

These findings suggest that CRP, IL-6, and ICAM-1 are molecular markers associated with atherosclerosis and its progression. IL-6 showed more consistent results and stronger independent predictive value than other inflammatory markers.

Topics & Keywords

Peripheral Artery Disease Management Adipokines, Inflammation, and Metabolic Diseases Lymphatic System and Diseases

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Circulation

Volume 112, Issue 7, pp. 976-983

DOI: 10.1161/circulationaha.104.513085

Field-Weighted Citation Impact: 31.45