Combination Antiretroviral Strategies for the Treatment of Pregnant HIV-1–Infected Women and Prevention of Perinatal HIV-1 Transmission

2002896 citationsJournal Article

Authors

Ellen Cooper · Eunice Kennedy Shriver National Institute of Child Health and Human Development

Manhattan Charurat · Institute of Human Virology

Lynne Mofenson · Eunice Kennedy Shriver National Institute of Child Health and Human Development

I. Celine Hanson · Baylor College of Medicine

Jane Pitt · Columbia University

Clemente Díaz · State University of New York

Karen Hayani

Abstract

Levels of HIV-1 RNA at delivery and prenatal antiretroviral therapy were independently associated with transmission. The protective effect of therapy increased with the complexity and duration of the regimen. HAART was associated with the lowest rates of transmission.

Topics & Keywords

HIV/AIDS Research and Interventions HIV Research and Treatment HIV/AIDS drug development and treatment

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: JAIDS Journal of Acquired Immune Deficiency Syndromes

Volume 29, Issue 5, pp. 484-494

DOI: 10.1097/00126334-200204150-00009

Field-Weighted Citation Impact: 24.89