Changes in Intestinal Morphology and Permeability in the BioBreeding Rat Before the Onset of Type 1 Diabetes

2005157 citationsJournal Article

Authors

Josef Neu · University of Florida

Christopher M Reverte · University of Florida Health

Amy D. Mackey · University of Florida Health

Kellym Liboni · University of Florida Health

Lauren M Tuhacek‐Tenace · Biomedical Research Models (United States)

Marguerite Hatch · University of Florida

Li Nan

Abstract

In a genetically susceptible rodent model of diabetes, early increased intestinal permeability might allow unregulated passage of environmental antigens that could potentially trigger the autoimmune response leading to type 1 diabetes.

Topics & Keywords

Diabetes and associated disorders Diet and metabolism studies Pancreatic function and diabetes

Publication Details

Published in: Journal of Pediatric Gastroenterology and Nutrition

Volume 40, Issue 5, pp. 589-595

DOI: 10.1097/01.mpg.0000159636.19346.c1

Field-Weighted Citation Impact: 2.53

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Changes in Intestinal Morphology and Permeability in the BioBreeding Rat Before the Onset of Type 1 Diabetes

Authors

Abstract

Topics & Keywords

Publication Details