Pulmonary Arterial Hypertension in Patients Treated by Dasatinib

2012639 citationsJournal Article

Authors

David Montani

Emmanuel Bergot

Abstract

Dasatinib may induce severe precapillary PH fulfilling the criteria of pulmonary arterial hypertension, thus suggesting a direct and specific effect of dasatinib on pulmonary vessels. Improvement is usually observed after withdrawal of dasatinib.

Topics & Keywords

Pulmonary Hypertension Research and Treatments Chronic Myeloid Leukemia Treatments Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Circulation

Volume 125, Issue 17, pp. 2128-2137

DOI: 10.1161/circulationaha.111.079921

Field-Weighted Citation Impact: 51.03