Effects of illness duration and treatment resistance on grey matter abnormalities in majordepression

201386 citationsJournal Articlebronze Open Access

Authors

Maria Serra-Blasco · Port d'Informació Científica

Marı́a J. Portella · Centro de Investigación Biomédica en Red de Salud Mental

Beatriz Gómez‐Ansón · Centro de Investigación Biomédica en Red

Javier de Diego-Adeliño · Hospital de Sant Pau

Yolanda Vives‐Gilabert · Port d'Informació Científica

Dolors Puigdemont · Universitat Autònoma de Barcelona

Ester Granell

Abstract

Frontotemporolimbic areas are smaller in the patients with severe depression and are associated with duration of illness, but not with medication patterns, suggesting negative effects of long-lasting major depressive disorder on grey matter.

Topics & Keywords

Functional Brain Connectivity Studies Treatment of Major Depression Transcranial Magnetic Stimulation Studies

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: The British Journal of Psychiatry

Volume 202, Issue 6, pp. 434-440

DOI: 10.1192/bjp.bp.112.116228

Field-Weighted Citation Impact: 3.27