Cardiac gene expression of atrial natriuretic peptide and brain natriuretic peptide in trisomic fetuses

199670 citationsJournal Article

Authors

Jonathan Hyett

Maria de Lourdes Brizot · King's College Hospital

C VONKAISENBERG · Harris Birthright Research Centre for Fetal Medicine

Andrew T. McKie · King's College Hospital

Farzin Farzaneh · King's College Hospital

K. H. Nicolaides · Harris Birthright Research Centre for Fetal Medicine

Abstract

These data demonstrate that atrial natriuretic peptide and brain natriuretic peptide genes are transcribed prenatally, and the findings in trisomic fetuses suggest that the increased translucency of trisomic fetuses may be the consequence of heart failure.

Topics & Keywords

Prenatal Screening and Diagnostics Congenital Heart Disease Studies Congenital Diaphragmatic Hernia Studies

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Obstetrics and Gynecology

Volume 87, Issue 4, pp. 506-510

DOI: 10.1016/0029-7844(95)00486-6

Field-Weighted Citation Impact: 6.50