Clinical Trial of Lamivudine in Children with Chronic Hepatitis B

2002318 citationsJournal Articlebronze Open Access

Authors

Maureen M. Jonas · Boston Children's Museum

Deirdre A. Kelley · Diana Princess of Wales Hospital

J. Mizerski · John Paul II Hospital

Isabel Badía · Hospital General de Niños Ricardo Gutierrez

Jorge Areias · Hospital de Santo António

Kathleen B. Schwarz · Johns Hopkins University

Nancy Little

Abstract

In children with chronic hepatitis B, 52 weeks of treatment with lamivudine was associated with a significantly higher rate of virologic response than was placebo.

Topics & Keywords

Hepatitis B Virus Studies Hepatitis C virus research HIV/AIDS drug development and treatment

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 346, Issue 22, pp. 1706-1713

DOI: 10.1056/nejmoa012452

Field-Weighted Citation Impact: 15.84