Inhaled Nitric Oxide Selectively Reverses Human Hypoxic Pulmonary Vasoconstriction without Causing Systemic Vasodilation

1993462 citationsJournal Articlebronze Open Access

Authors

Göran Hedenstierna · Uppsala University Hospital

Warren M. Zapol · Massachusetts General Hospital

Abstract

Inhalation of 40 ppm NO selectively induced pulmonary vasodilation and reversed hypoxic pulmonary vasoconstriction in healthy humans without causing systemic vasodilation.

Topics & Keywords

Nitric Oxide and Endothelin Effects Pulmonary Hypertension Research and Treatments Cardiovascular and Diving-Related Complications

Publication Details

Published in: Anesthesiology

Volume 78, Issue 3, pp. 427-435

DOI: 10.1097/00000542-199303000-00005

Field-Weighted Citation Impact: 24.57

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Inhaled Nitric Oxide Selectively Reverses Human Hypoxic Pulmonary Vasoconstriction without Causing Systemic Vasodilation

Authors

Abstract

Topics & Keywords

Publication Details