Cyclosporine A sensitizes the kidney to tubulointerstitial fibrosis induced by renal warm ischemia

200417 citationsJournal Article

Authors

Ahmed Ahmed · Northern General Hospital

Linghong Huang · Northern General Hospital

Andrew T. Raftery · Northern General Hospital

Aimun Ahmed · Northern General Hospital

Hossam A. H. Fahmy · Northern General Hospital

A. Meguid El Nahas · Northern General Hospital

J. Haylor

Abstract

In the rat, CsA can sensitize the kidney to fibrosis induced by renal warm ischemia. In renal transplantation, when cadaveric donor kidneys have been subjected to a period of warm ischemia, CsA may be an inappropriate choice for immunosuppressive therapy.

Topics & Keywords

Renal and Vascular Pathologies Renal Transplantation Outcomes and Treatments Organ Transplantation Techniques and Outcomes

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Transplantation

Volume 77, Issue 5, pp. 686-692

DOI: 10.1097/01.tp.0000113850.34945.dc

Field-Weighted Citation Impact: 1.72