Brain Morphology in Children with Epilepsy and ADHD

201441 citationsJournal Articlegold Open Access

Authors

Ricardo Lutzky Saute · Pontifícia Universidade Católica do Rio Grande do Sul

Kevin Dabbs · University of Wisconsin–Madison

Jana E. Jones · University of Wisconsin–Madison

Daren C. Jackson · University of Wisconsin–Madison

Michael Seidenberg · Rosalind Franklin University of Medicine and Science

Bruce P. Hermann · University of Wisconsin–Madison

Abstract

Children with epilepsy and comorbid ADHD exhibited a pattern of bilateral and widespread decreased cortical thickness as well as decreased volume of subcortical structures and brainstem. These anatomic abnormalities were evident early in the course of epilepsy suggesting the presence of antecedent neurodevelopmental changes, the course of which remains to be determined.

Topics & Keywords

Attention Deficit Hyperactivity Disorder Epilepsy research and treatment Functional Brain Connectivity Studies

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: PLoS ONE

Volume 9, Issue 4, pp. e95269-e95269

DOI: 10.1371/journal.pone.0095269

Field-Weighted Citation Impact: 3.10