Design, synthesis and biological evaluation of thiourea and nicotinamide-containing sorafenib analogs as antitumor agents

201520 citationsJournal Article

Authors

Abstract

Thiourea and nicotinamide-containing sorafenib analogs with better antiproliferative and anti-angiogenic activities than sorafenib were well designed and synthesized.

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Hepatocellular Carcinoma Treatment and Prognosis PI3K/AKT/mTOR signaling in cancer Cancer Mechanisms and Therapy

Publication Details

Published in: MedChemComm

Volume 6, Issue 5, pp. 867-870

DOI: 10.1039/c4md00536h

Field-Weighted Citation Impact: 0.78

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Design, synthesis and biological evaluation of thiourea and nicotinamide-containing sorafenib analogs as antitumor agents

Authors

Abstract

Topics & Keywords

Publication Details