Single-Dose Azithromycin versus Penicillin G Benzathine for the Treatment of Early Syphilis

2005297 citationsJournal Articlebronze Open Access

Authors

Gabriele Riedner · University of London

Mary Rusizoka

Jim Todd · London School of Hygiene & Tropical Medicine

Leonard Maboko · Mbeya University of Science and Technology

Michael Höelscher · Ludwig-Maximilians-Universität München

Donan Mmbando

Eleuter Samky · Mbeya University of Science and Technology

Eligius Lyamuya

Abstract

Single-dose oral azithromycin is effective in treating syphilis and may be particularly useful in developing countries in which the use of penicillin G benzathine injections is problematic. However, recent reports of azithromycin-resistant Treponema pallidum in the United States indicate the importance of continued monitoring for resistance.

Topics & Keywords

Syphilis Diagnosis and Treatment Reproductive tract infections research Immunodeficiency and Autoimmune Disorders

Publication Details

Published in: New England Journal of Medicine

Volume 353, Issue 12, pp. 1236-1244

DOI: 10.1056/nejmoa044284

Field-Weighted Citation Impact: 10.52

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Single-Dose Azithromycin versus Penicillin G Benzathine for the Treatment of Early Syphilis

Authors

Abstract

Topics & Keywords

Publication Details