A homozygous nonsense mutation (c.214C→A) in the biliverdin reductase alpha gene ( <i>BLVRA)</i> results in accumulation of biliverdin during episodes of cholestasis

This is the first report of a homozygous BLVRA inactivating mutation indicating that the complete absence of BVRα activity is a non-lethal condition, the most evident phenotypic characteristic of which is the appearance of green jaundice accompanying cholestasis episodes.