Association of Galectin-3 and Fibrosis Markers with Long-Term Cardiovascular Outcomes in Patients with Heart Failure, Left Ventricular Dysfunction, and Dyssynchrony: Insights from the CARE-HF (Cardiac Resynchronization in Heart Failure) Trial

2011227 citationsJournal Article

Authors

Natalia López‐Andrés · Centre d’Investigation Clinique Innovation Technologique de Nancy

Patrick Rossignol · Institut de Cancérologie de Lorraine

Wafae Iraqi · Institut de Cancérologie de Lorraine

Renaud Fay · Université de Lorraine

Josette Nuée · Centre d’Investigation Clinique Innovation Technologique de Nancy

Stefano Ghio · Policlinico San Matteo Fondazione

John G.F. Cleland

Abstract

Increased Gal-3 and PIIINP, and low MMP-1 are associated with adverse long-term cardiovascular outcomes but did not predict response to CRT. CRT did not favourably affect serum concentrations of ECCM markers.

Topics & Keywords

Galectins and Cancer Biology Cardiac Structural Anomalies and Repair Cardiac Fibrosis and Remodeling

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: European Journal of Heart Failure

Volume 14, Issue 1, pp. 74-81

DOI: 10.1093/eurjhf/hfr151

Field-Weighted Citation Impact: 7.65