Integrative Analysis of Head and Neck Cancer Identifies Two Biologically Distinct HPV and Three Non-HPV Subtypes

2014379 citationsJournal Article

Authors

Michaela K. Keck

Zhixiang Zuo

Abstract

Our five-subtype classification provides a comprehensive overview of HPV(+) as well as HPV(-) HNSCC biology with significant translational implications for biomarker development and personalized care for patients with HNSCC.

Topics & Keywords

Head and Neck Cancer Studies RNA modifications and cancer Cancer-related gene regulation

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Clinical Cancer Research

Volume 21, Issue 4, pp. 870-881

DOI: 10.1158/1078-0432.ccr-14-2481

Field-Weighted Citation Impact: 26.39