Myopodin Methylation is Associated With Clinical Outcome in Patients With T1G3 Bladder Cancer

201037 citationsJournal Article

Authors

M. Álvarez-Múgica · Hospital Universitario Central de Asturias

Virginia Cebrián · Spanish National Cancer Research Centre

J.M. Fernández Gómez · Hospital Universitario Central de Asturias

Florentino Fresno · Hospital Universitario Central de Asturias

Safwan Escaf · Hospital Universitario Central de Asturias

Marta Sänchez‐Carbayo · Spanish National Cancer Research Centre

Abstract

Epigenetic analysis revealed that myopodin methylation was associated with tumor aggressiveness and clinical outcome in patients with T1G3 disease. Myopodin methylation distinguished patients responding to bacillus Calmette-Guerin from those who may require a more aggressive therapeutic approach.

Topics & Keywords

Bladder and Urothelial Cancer Treatments Urinary and Genital Oncology Studies Epigenetics and DNA Methylation

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: The Journal of Urology

Volume 184, Issue 4, pp. 1507-1513

DOI: 10.1016/j.juro.2010.05.085

Field-Weighted Citation Impact: 3.45