Profound Cardioprotection With Chloramphenicol Succinate in the Swine Model of Myocardial Ischemia-Reperfusion Injury

2010152 citationsJournal Article

Authors

Javier A. Sala‐Mercado · Cardiovascular Research Center

Joseph M. Wider · Cardiovascular Research Center

Vishnu Undyala · Cardiovascular Research Center

Salik Jahania · Cardiovascular Research Center

Wonsuk Yoo · Cardiovascular Research Center

Robert M. Mentzer · Cardiovascular Research Center

Roberta A. Gottlieb

Abstract

Our results demonstrate attenuation of ischemia-reperfusion injury with CAPS and are consistent with the concept that induction of autophagy may provide a novel strategy to confer cardioprotection.

Topics & Keywords

Autophagy in Disease and Therapy Advanced Glycation End Products research Cardiac Ischemia and Reperfusion

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Circulation

Volume 122, Issue 11_suppl_1, pp. S179-84

DOI: 10.1161/circulationaha.109.928242

Field-Weighted Citation Impact: 7.39