Hepatic ‘stem cell’ malignancies in adults: four cases

2003209 citationsJournal Article

Authors

Neil D. Theise · New York University

Jinfeng Yao · Columbia University Irving Medical Center

Kenichi Harada · Kanazawa University

Prodromos Hytiroglou · Aristotle University of Thessaloniki

B Portmann · King's College Hospital

Swan N. Thung · Mount Sinai Medical Center

Wilson M. S. Tsui

Abstract

We suggest that these tumours are of hepatic progenitor cell origin, supporting the concepts that human hepatocarcinogenesis can be based on transformation of progenitor cells and that such a process may underlie development of some mixed hepatocellular/cholangiocarcinomas and dysplastic nodules.

Topics & Keywords

Cholangiocarcinoma and Gallbladder Cancer Studies Congenital Anomalies and Fetal Surgery Liver physiology and pathology

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Histopathology

Volume 43, Issue 3, pp. 263-271

DOI: 10.1046/j.1365-2559.2003.01707.x

Field-Weighted Citation Impact: 10.05