Injectable Collagenase Clostridium Histolyticum for Dupuytren's Contracture

2009692 citationsJournal Articlebronze Open Access

Authors

Lawrence C. Hurst · Stony Brook University

Marie A. Badalamente · Stony Brook Medicine

Vincent R. Hentz · Stanford Health Care

Robert N. Hotchkiss · Hospital for Special Surgery

F. Thomas D. Kaplan · Indiana Hand to Shoulder Center

Roy A. Meals · Los Angeles City College

Theodore M. Smith

Abstract

Collagenase clostridium histolyticum significantly reduced contractures and improved the range of motion in joints affected by advanced Dupuytren's disease. (ClinicalTrials.gov number, NCT00528606.)

Topics & Keywords

Dupuytren's Contracture and Treatments Orthopedic Surgery and Rehabilitation Nail Diseases and Treatments

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 361, Issue 10, pp. 968-979

DOI: 10.1056/nejmoa0810866

Field-Weighted Citation Impact: 29.62