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Rational design of cationic lipids for siRNA delivery

20101,751 citationsJournal Article

Authors

Sean C. Semple · Arbutus Biopharma (Canada)

Akin Akinc · Alnylam Pharmaceuticals (United States)

Jianxin Chen · Arbutus Biopharma (Canada)

Ammen P. Sandhu · Arbutus Biopharma (Canada)

Barbara L. Mui · Arbutus Biopharma (Canada)

Connie K Cho · Arbutus Biopharma (Canada)

Topics & Keywords

RNA Interference and Gene Delivery Advanced biosensing and bioanalysis techniques MicroRNA in disease regulation

Publication Details

Published in: Nature Biotechnology

Volume 28, Issue 2, pp. 172-176

DOI: 10.1038/nbt.1602

Field-Weighted Citation Impact: 40.84

Rational design of cationic lipids for siRNA delivery | Researchclopedia

· Alnylam Pharmaceuticals (United States)

Derrick Stebbing · Arbutus Biopharma (Canada)

Erin Crosley · Arbutus Biopharma (Canada)

Ed Yaworski · Arbutus Biopharma (Canada)

Ismail M. Hafez · University of British Columbia

J. Robert Dorkin · Alnylam Pharmaceuticals (United States)

June Qin · Alnylam Pharmaceuticals (United States)

Kieu Lam · Arbutus Biopharma (Canada)

Kallanthottathil G. Rajeev · Alnylam Pharmaceuticals (United States)

Kim F. Wong · University of British Columbia

Lloyd B. Jeffs · Arbutus Biopharma (Canada)

Lubomir V. Nechev · Alnylam Pharmaceuticals (United States)

Merete L. Eisenhardt · Arbutus Biopharma (Canada)

Muthusamy Jayaraman · Alnylam Pharmaceuticals (United States)

Mikameh Kazem · University of British Columbia

Martin A. Maier · Alnylam Pharmaceuticals (United States)

Masuna Srinivasulu · University of British Columbia

Michael J Weinstein · Alnylam Pharmaceuticals (United States)

Qingmin Chen · Alnylam Pharmaceuticals (United States)

Rene Alvarez · Alnylam Pharmaceuticals (United States)

Scott Barros · Alnylam Pharmaceuticals (United States)

Soma De · Alnylam Pharmaceuticals (United States)

Sandra K. Klimuk · Arbutus Biopharma (Canada)

Todd Borland · Alnylam Pharmaceuticals (United States)

Verbena Kosovrasti · Alnylam Pharmaceuticals (United States)

William Cantley · Alnylam Pharmaceuticals (United States)

Ying K. Tam · Arbutus Biopharma (Canada)

Muthiah Manoharan · Alnylam Pharmaceuticals (United States)

Marco A. Ciufolini · University of British Columbia

Mark A. Tracy · Alnylam Pharmaceuticals (United States)

Antonin de Fougerolles · Alnylam Pharmaceuticals (United States)

Ian MacLachlan · Arbutus Biopharma (Canada)

Pieter R. Cullis · University of British Columbia

Thomas D. Madden · Arbutus Biopharma (Canada)

Michael J. Hope · Arbutus Biopharma (Canada)