Pathogenic role of the CXCL16–CXCR6 pathway in rheumatoid arthritis

2005148 citationsJournal Article

Authors

Toshihiro Nanki · Tokyo Medical and Dental University

Takeshi Shimaoka · Kyoto University

Kenji Hayashida · Hoshigaoka Medical Center

Ken Taniguchi · Tokyo Metropolitan Bokutoh Hospital

Shin Yonehara · Kyoto University

Nobuyuki Miyasaka · Tokyo Medical and Dental University

Abstract

Our results indicate that CXCL16 plays an important role in T cell accumulation and stimulation in RA synovium and suggest that CXCL16 could be a target molecule in new therapies for RA.

Topics & Keywords

Chemokine receptors and signaling Immunotherapy and Immune Responses T-cell and B-cell Immunology

Publication Details

Published in: Arthritis & Rheumatism

Volume 52, Issue 10, pp. 3004-3014

DOI: 10.1002/art.21301

Field-Weighted Citation Impact: 4.94

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Pathogenic role of the CXCL16–CXCR6 pathway in rheumatoid arthritis

Authors

Abstract

Topics & Keywords

Publication Details