The histogenesis of cartilage and bone in the long bones of the embryonic fowl

Abstract The development and cytology of cartilage and bone in the limbs from the fifty‐second hour of incubation to the first day after hatching are described. The chief points of interest arising from this study are: (1) Chondroblasts when liberated during cartilage resorption die and disintegrate. (2) All the long bones possess structures which, though not undergoing independent ossification, are homologous with the mammalian epiphyses. (3) Endochondral ossification occurs only in the epiphyses and ends of the diaphyses. (4) The marrow cavity contains multinucleated giant cells which appear to be formed by the fusion of degenerating cells.