Suppression of Retinal Peroxisome Proliferator-Activated Receptor γ in Experimental Diabetes and Oxygen-Induced Retinopathy: Role of NADPH Oxidase

200978 citationsJournal Article

Authors

Amany Tawfik

Tammy Sanders

Khalid Kahook

Sara Akeel

Ahmed A. Elmarakby · Center for Vascular Biology Research

Mohamed Al‐Shabrawey · Augusta University

Abstract

Suppression of PPARgamma is involved in the pathogenesis of diabetic retinopathy and OIR. NADPH oxidase could be an upstream mediator of these changes.

Topics & Keywords

Retinal Diseases and Treatments Peroxisome Proliferator-Activated Receptors Neutrophil, Myeloperoxidase and Oxidative Mechanisms

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Investigative Ophthalmology & Visual Science

Volume 50, Issue 2, pp. 878-878

DOI: 10.1167/iovs.08-2005

Field-Weighted Citation Impact: 6.94