The Impact of Pharmacogenomics on Postoperative Nausea and Vomiting

2005190 citationsJournal Articlebronze Open Access

Authors

Keith Candiotti

David J. Birnbach · Beijing Obstetrics and Gynecology Hospital

David A. Lubarsky

Fani Nhuch · University of Miami

Aimee Kamat

Walter Koch · Roche (Switzerland)

Michele Nikoloff · Office of the Chief Scientist

Lin Wu

David Andrews

Abstract

Patients with three copies of the CYP2D6 gene, a genotype consistent with ultrarapid metabolism, or both have an increased incidence of ondansetron failure for the prevention of postoperative vomiting but not nausea.

Topics & Keywords

Nausea and vomiting management Anesthesia and Pain Management Anesthesia and Sedative Agents

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Anesthesiology

Volume 102, Issue 3, pp. 543-549

DOI: 10.1097/00000542-200503000-00011

Field-Weighted Citation Impact: 12.08