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ADVERTISEMENT RETURN TO ISSUEPREVReviewNEXTImpact of Natural Products on Developing New Anti-Cancer Agents†Gordon M. Cragg, Paul G. Grothaus, and David J. Newman*View Author Information Natural Products Branch, Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, NCI−Frederick, Fairview Center, Suite 206, P.O. Box B, Frederick, Maryland 21702-1201* To whom correspondence should be addressed. E-mail: [email protected]†This manuscript reflects the opinion of the authors, not necessarily those of the United States Government.Cite this: Chem. Rev. 2009, 109, 7, 3012–3043Publication Date (Web):May 7, 2009Publication History Received16 January 2009Published online7 May 2009Published inissue 8 July 2009https://pubs.acs.org/doi/10.1021/cr900019jhttps://doi.org/10.1021/cr900019jreview-articleACS PublicationsCopyright © This article not subject to U.S. Copyright. Published 2009 by the American Chemical SocietyRequest reuse permissionsArticle Views24433Altmetric-Citations991LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Assays,Inhibitors,Peptides and proteins,Pharmaceuticals,Polarization Get e-Alerts