Current status of interleukin-10 and regulatory T-cells in cancer

2013284 citationsReview

Authors

Kristen L. Dennis · Robert H. Lurie Comprehensive Cancer Center of Northwestern University

Nichole R. Blatner · Robert H. Lurie Comprehensive Cancer Center of Northwestern University

Khashayarsha Khazaie · Weatherford College

Abstract

IL-10 functions at the cross-roads of immune stimulation and immune suppression in cancer. Immunological mechanisms of action of IL-10 can be ultimately exploited to develop novel and effective cancer therapies.

Topics & Keywords

Immunotherapy and Immune Responses Cancer Immunotherapy and Biomarkers Immune Cell Function and Interaction

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Current Opinion in Oncology

Volume 25, Issue 6, pp. 637-645

DOI: 10.1097/cco.0000000000000006

Field-Weighted Citation Impact: 6.31